The expression of neuroligins or neurexins in cultured nonneuronal cells demonstrates that these molecules are sufficient to induce presynaptic specializations in mouse hippocampal neurons in vitro. Rare mutations in neuroglian and neurexin genes have been associated with familial autism spectrum disorders. However, even mice lacking all three neuroligin genes still have the normal number of synapses. Propose some possible explanations to reconcile these findings and suggest some experiments that could be performed to distinguish between them.
Correct Answer:
Verified
View Answer
Unlock this answer now
Get Access to more Verified Answers free of charge
Q1: What effects would you expect to see
Q2: If a mutation were to occur to
Q3: What might you expect to observe if
Q5: Expressing Lin44 more anteriorly also expands the
Q6: The loss of Numb in the Drosophila
Q7: Motor neurons 1 and 2 start out
Q8: Dendritic tiling in the vertebrate retina (mutual
Q9: Which of the following are sufficient for
Q10: Axon pruning in Drosophila mushroom body neurons
Q11: In early dorsoventral patterning studies, researchers found
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents