Question 1

A macrophage was isolated and analyzed for major histocompatibility complex.Which of the following would be expected?
A) MHC I only
B) MHC II only
C) MHC I and II
D) Neither MHC I or MHC II

Accepted Answer

MCH I and II would be expected.
MCH I and II would be expected.
MCH I and II would be expected.
Both MCH I and II would be expected.

Question 2

Which of the following statements indicates more teaching is needed regarding secondary lymph organs? ________is/are a secondary lymph organ.
A) The spleen
B) Peyer patches
C) Adenoids
D) The liver

Accepted Answer

The liver is not a secondary lymph organ.
The spleen is a secondary lymphoid organ.
Peyer patches are a secondary lymph organ.
The adenoids are a secondary lymph organ.

Question 3

A 23-year-old pregnant female visits her primary care provider for her final prenatal checkup.The primary care provider determines that the fetus has developed an infection in utero.Which of the following would be increased in the fetus at birth?
A) IgG
B) IgA
C) IgM
D) IgD

Accepted Answer

IgM is synthesized early in neonatal life,and its synthesis may be increased as a response to infection in utero.
IgM,not IgG,is synthesized early in neonatal life,and its synthesis may be increased as a response to infection in utero.
IgM,not IgA,is synthesized early in neonatal life,and its synthesis may be increased as a response to infection in utero.
IgM,not IgD,is synthesized early in neonatal life,and its synthesis may be increased as a response to infection in utero.

Question 4

A 10-year-old male is stung by a bee while playing in the yard.He experiences a severe allergic reaction and has to go to the ER.The nurse providing care realizes this reaction is the result of:
A) Toxoids
B) IgA
C) IgE
D) IgM

Accepted Answer

IgE is normally at low concentrations in the circulation.It has very specialized functions as a mediator of many common allergic responses.
IgE,not toxoids,is the mediator of common allergic response.
IgE,not IgA,is the mediator of common allergic response.
IgE,not IgM,is the mediator of common allergic response.

Question 5

A 6-year-old female is diagnosed with a bacterial infection of the respiratory system.Which of the following will most likely try to fight the antigen?
A) Antibodies
B) Cytotoxic T cells
C) Self-antigens
D) Helper T cells

Accepted Answer

Antibodies are produced by plasma cells that mature from lymphocytes,called B lymphocytes (B cells),in response to an antigen.
Antibodies are produced by plasma cells that mature from lymphocytes,called B lymphocytes (B cells),in response to an antigen.Cytotoxic T cells do not respond to antigens.
Antibodies are produced by plasma cells that mature from lymphocytes,called B lymphocytes (B cells),in response to an antigen.Self-antigens do not respond to antigens.
Antibodies are produced by plasma cells that mature from lymphocytes,called B lymphocytes (B cells),in response to an antigen.Helper T cells do not respond to antigens.

Question 6

The predominant antibody of a typical primary immune response is:
A) IgG
B) IgM
C) IgA
D) IgE

Accepted Answer

IgM is the largest immunoglobulin and is the first antibody produced during the initial,or primary,response to antigen.
IgM,not IgG,is the largest immunoglobulin and is the first antibody produced during the initial,or primary,response to antigen.
IgM,not IgA,is the largest immunoglobulin and is the first antibody produced during the initial,or primary,response to antigen.
IgM,not IgE,is the largest immunoglobulin and is the first antibody produced during the initial,or primary,response to antigen.

Question 7

After a patient is exposed to a specific antigen,B cells will differentiate into:
A) B cytotoxic cells
B) Clonal equivalents
C) Plasma cells
D) Bursal cells

Accepted Answer

The B cell differentiates into plasma cells.
The B cell differentiates into plasma cells,not B cytotoxic cells.
The B cell differentiates into plasma cells,not clonal equivalents.
The B cell differentiates into plasma cells,not bursal cells.

Question 8

An immunologist has isolated a molecule from the human body to study.It is found to react with antibodies on B cells.Further testing reveals that the molecule is large and chemically diverse.What type of molecule is the immunologist studying?
A) Antigen
B) Immunogen
C) Epitope
D) Paratope

Accepted Answer

Antibodies react with antigens.
Antibodies react with antigens,not immunogen.
Antibodies react with antigens,not epitopes.
Antibodies react with antigens,not paratopes.

Question 9

Which of the following characteristics is shared by both the secretory and systemic immune systems?
A) Lymphocytic paths of migration
B) Neutralization following antigen-antibody binding
C) Timing of response
D) Location of response

Accepted Answer

Direct effects result from the binding of antibody directly to a harmful antigen or infectious agent.These include inhibition of processes that are necessary for infection,such as the reaction of an infectious agent with a particular cell in the body or neutralization of harmful bacterial toxins.
The effect of the immune system is neutralization,not lymphocytic paths of migration.
The effect of the immune system is neutralization,not timing of response.
The effect of the immune system is neutralization,not location of response.

Question 10

A 25-year-old female has sexual relations with her boyfriend.Later she is told that the boyfriend is infected with Neisseria gonorrhoeae.Testing reveals that she does not have the disease.How is it possible that she did not contract the disease?
A) Antibodies covered sites of attachment.
B) She was vaccinated against it.
C) Platelets provided protection.
D) IgE was released.

Accepted Answer

Some bacteria,such as Neisseria gonorrhoeae that causes gonorrhea,must attach to specific sites on urogenital epithelial cells.Antibodies may protect the host by covering sites on the microorganism that are needed for attachment,thereby preventing infection.
The patient did not contract the disease because antibodies covered sites of attachment,not because of vaccination.
The patient did not contract the disease because antibodies covered sites of attachment,not because of platelets.
The patient did not contract the disease because antibodies covered sites of attachment,not because of IgE release.

Question 11

A patient has done research on monoclonal antibodies on the Internet.Which statement indicates a correct understanding? Pure monoclonal antibodies are produced by:
A) T lymphocytes
B) Bone marrow
C) Laboratories
D) Fetuses

Accepted Answer

Monoclonal antibodies are produced in the laboratory from one B cell that has been cloned; thus,the entire antibody is of the same class,specificity,and function.
Monoclonal antibodies are produced in the laboratory,not by T lymphocytes.
Monoclonal antibodies are produced in the laboratory,not by the bone marrow.
Monoclonal antibodies are produced in the laboratory,not by the fetus.

Question 12

Which portion of the antibody is responsible for the biologic functions of antibodies?
A) Heavy chain
B) Variable region
C) Fc portion
D) Epitope

Accepted Answer

The Fc portion is responsible for most of the functions of antibodies.
The Fc portion is responsible for most of the functions of antibodies,not the heavy chain.
The Fc portion is responsible for most of the functions of antibodies,not the variable region.
The Fc portion is responsible for most of the functions of antibodies,not the epitope.

Question 13

Which of the following is responsible for initiating clonal selection?
A) T cells
B) B cells
C) Antigens
D) Lymphocytes

Accepted Answer

The lymphocytes remain dormant until an antigen initiates clonal selection.
T cells are part of the immune response,but do not initiate clonal selection.
B cells are antibodies.
Lymphocytes are released into the circulation as immature cells that react with antigens.

Question 14

When the immunoglobulin crosses the placenta,what type of immunity does the fetus receive?
A) Active
B) Passive
C) Innate
D) Cell-mediated

Accepted Answer

Maternal antibodies that pass across the placenta into the fetus before birth provide passive systemic immunity.
Maternal antibodies that pass across the placenta into the fetus before birth provide passive systemic immunity,not active immunity.
Maternal antibodies that pass across the placenta into the fetus before birth provide passive systemic immunity,not innate immunity.
Maternal antibodies that pass across the placenta into the fetus before birth provide passive systemic immunity,not cell-mediated immunity.

Question 15

An experiment is designed to determine specific cell types involved in cell-mediated immune response.The experimenter is interested in finding cells that attack cells that have specific antigens.Which cells should be isolated?
A) Lymphokine-producing cells
B) Cytotoxic T cells
C) Helper T cells
D) Macrophages

Accepted Answer

Cell-mediated immunity is driven by T-cytotoxic (Tc)cells that attack antigens directly and destroy cells that bear foreign antigens.
Cell-mediated immunity is driven by T-cytotoxic (Tc)cells,not lymphokine-producing cells,that attack antigens directly and destroy cells that bear foreign antigens.
Cell-mediated immunity is driven by T-cytotoxic (Tc)cells,not helper T cells,that attack antigens directly and destroy cells that bear foreign antigens.
Cell-mediated immunity is driven by T-cytotoxic (Tc)cells,not macrophages,that attack antigens directly and destroy cells that bear foreign antigens.

Question 16

After teaching the students about B cells,which statement indicates teaching was successful? B cells are originally derived from cells of the:
A) Bone marrow
B) Lymph nodes
C) Gut-associated lymphoid tissue
D) Thymus

Accepted Answer

B cells are derived from the bone marrow.
B cells are derived from the bone marrow,not the lymph nodes.
B cells are derived from the bone marrow,not the gut-associated lymphoid tissue.
B cells are derived from the bone marrow,not the thymus.

Question 17

Which statement indicates a correct understanding of antibodies? The most abundant class of antibody in the serum is:
A) IgG
B) IgM
C) IgA
D) IgE

Accepted Answer

IgG is the most abundant class of immunoglobulins,constituting 80% to 85% of the immunoglobulins in the blood.
IgG is the most abundant class of immunoglobulins,not IgM.
IgG is the most abundant class of immunoglobulins,not IgA.
IgG is the most abundant class of immunoglobulins,not IgE.

Question 18

An experiment is carried out to characterize newly discovered immunoglobulins.Specificity of the amino acids within the immunoglobulin could be determined by studying the:
A) C region of the light chain
B) C region of the H chain
C) Complementary-determining region (CDR)
D) Framework regions

Accepted Answer

The amino acid differences are clustered into three areas in the variable region.These three areas are called CDRs.
The amino acid differences are clustered into three areas in the variable region.These three areas are called CDRs,not the C region of the light chain.
The amino acid differences are clustered into three areas in the variable region.These three areas are called CDRs,not the C region of the H chain.
The amino acid differences are clustered into three areas in the variable region.These three areas are called CDRs,not the framework regions.

Question 19

An immunology nurse is caring for a patient.While planning care,which principle will the nurse remember? The primary role of IgA1 is to prevent infections in the:
A) Blood
B) Kidneys
C) Lungs
D) Mucous membranes

Accepted Answer

IgA1 is found predominantly in the blood.
IgA1 is found predominantly in the blood,not the kidneys.
IgA1 is found predominantly in the blood,not the lungs.
IgA1 is found predominantly in the blood,not the mucous membranes.

Question 20

A 20-year-old female is applying for nursing school and is required to be tested for immunity against several illnesses.Testing that looks at which of the following would be the best to determine immunity?
A) Culture and sensitivity
B) Agglutination
C) Precipitation
D) Titer

Accepted Answer

The amount of antibody in a serum sample is referred to as the titer; a higher titer indicates more antibodies.
Culture and sensitivity determine the type of organism that causes an infection,and sensitivity identifies the antibody it is sensitive to.
The amount of antibody in a serum sample is referred to as the titer,not agglutination.
The amount of antibody in a serum sample is referred to as the titer,not precipitation.

Quiz 6: Adaptive Immunity

A macrophage was isolated and analyzed for major histocompatibility complex.Which of the following would be expected?

Which of the following statements indicates more teaching is needed regarding secondary lymph organs? ________is/are a secondary lymph organ.

A 23-year-old pregnant female visits her primary care provider for her final prenatal checkup.The primary care provider determines that the fetus has developed an infection in utero.Which of the following would be increased in the fetus at birth?

A 10-year-old male is stung by a bee while playing in the yard.He experiences a severe allergic reaction and has to go to the ER.The nurse providing care realizes this reaction is the result of:

A 6-year-old female is diagnosed with a bacterial infection of the respiratory system.Which of the following will most likely try to fight the antigen?

The predominant antibody of a typical primary immune response is:

After a patient is exposed to a specific antigen,B cells will differentiate into:

An immunologist has isolated a molecule from the human body to study.It is found to react with antibodies on B cells.Further testing reveals that the molecule is large and chemically diverse.What type of molecule is the immunologist studying?

Which of the following characteristics is shared by both the secretory and systemic immune systems?

A 25-year-old female has sexual relations with her boyfriend.Later she is told that the boyfriend is infected with Neisseria gonorrhoeae.Testing reveals that she does not have the disease.How is it possible that she did not contract the disease?

A patient has done research on monoclonal antibodies on the Internet.Which statement indicates a correct understanding? Pure monoclonal antibodies are produced by:

Which portion of the antibody is responsible for the biologic functions of antibodies?

Which of the following is responsible for initiating clonal selection?

When the immunoglobulin crosses the placenta,what type of immunity does the fetus receive?

An experiment is designed to determine specific cell types involved in cell-mediated immune response.The experimenter is interested in finding cells that attack cells that have specific antigens.Which cells should be isolated?

After teaching the students about B cells,which statement indicates teaching was successful? B cells are originally derived from cells of the:

Which statement indicates a correct understanding of antibodies? The most abundant class of antibody in the serum is:

An experiment is carried out to characterize newly discovered immunoglobulins.Specificity of the amino acids within the immunoglobulin could be determined by studying the:

An immunology nurse is caring for a patient.While planning care,which principle will the nurse remember? The primary role of IgA1 is to prevent infections in the:

A 20-year-old female is applying for nursing school and is required to be tested for immunity against several illnesses.Testing that looks at which of the following would be the best to determine immunity?