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What Is the Mechanism of Decitabine Treatment for Sickle Cell

Question 8

Multiple Choice

What is the mechanism of decitabine treatment for sickle cell disease?


A) Incorporation of decitabine into DNA causes γ-globin promoter hypermethylation
B) Incorporation of decitabine into DNA causes γ-globin promoter hypomethylation
C) Incorporation of decitabine into RNA increases γ-globin translation
D) Incorporation of decitabine into RNA decreases γ-globin translation
E) Incorporation of decitabine into HbS increases its function

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