A 19-Year-Old Woman Comes to the Student Health Center After

A 19-year-old woman comes to the student health center after a sexual assault 2 days ago.  She has no fevers, chills, abdominal pain, or abnormal vaginal discharge.  The patient was sexually assaulted by a man she has seen multiple times, who also attends the university.  Menses are regular and occur every 29 days; her last menstrual period was 2 weeks ago.  She has no known medical conditions and has had no surgeries.  The patient takes no medications and has no drug allergies.  She smokes cigarettes and drinks alcohol socially.  There is no family history of any illness.  She is sexually active with a long-term male partner, and they use condoms for contraception.  The patient has no history of sexually transmitted infections.  Temperature is 36.7 C (98 F) , blood pressure is 110/70 mm Hg, and pulse is 65/min.  BMI is 20 kg/m².  The abdomen is soft and nontender, with no palpable masses.  Bruises and abrasions are present over the inner thighs, perineum, and vulva.  Pelvic examination reveals a friable cervix that bleeds easily on contact.  The vaginal mucosa is erythematous with no evidence of hematoma.  The uterus is small and nontender on bimanual examination; no adnexal masses are palpated.  Microscopy shows an abundance of polymorphonuclear leukocytes.  Urine pregnancy test is negative. The patient undergoes a sexually transmitted infection workup, including viral hepatitis, HIV, syphilis, chlamydia, and gonorrhea.  She completed a hepatitis B vaccination series prior to college, and all other vaccines are up to date.  Based on her history and examination, which of the following medications should be administered?

A) Ceftriaxone, azithromycin
B) Ceftriaxone, azithromycin, hepatitis B immune globulin
C) Ceftriaxone, azithromycin, hepatitis B immune globulin, tenofovir-emtricitabine with raltegravir
D) Ceftriaxone, azithromycin, penicillin
E) Ceftriaxone, azithromycin, tenofovir-emtricitabine with raltegravir