The primary difference between an experimental (randomized) clinical trial and other observational study designs in epidemiology is that in an experimental trial, the

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In an experimental (randomized) clinical trial, the investigator determines who is and who is not exposed to the intervention or treatment being studied, whereas in other observational study designs, such as cohort and case-control studies, the exposure status is determined based on factors outside of the investigator's control, such as natural occurrence or self-selection by study participants. Additionally, in an experimental trial, participants are typically assigned to either a treatment or control group randomly, whereas other observational studies often involve selecting groups based on their exposure status or other characteristics.

The Primary Difference Between an Experimental (Randomized) Clinical Trial and Other