A group of scientists is working on new osteoporosis drugs. They are testing Substance X, a new drug that exhibits the following metabolic effects when administered via infusion in varying doses (as shown in the graphs below). Which of the following most closely resembles the metabolic effects of Substance X?

Question

A group of scientists is working on new osteoporosis drugs. They are testing Substance X, a new drug that exhibits the following metabolic effects when administered via infusion in varying doses (as shown in the graphs below).  Which of the following most closely resembles the metabolic effects of Substance X?

Quizplus · Accepted Answer

Eductional Objective: PTH causes increased bone resorption, elevated serum calcium levels, and increased renal phosphate excretion. Chronically elevated PTH levels increase the risk of osteoporosis. Intermittent administration of recombinant PTH analogs (for example, teriparatide) causes a greater increase in osteoblast activity in proportion to osteoclast activity, resulting in a net increase in bone formation.

A Group of Scientists Is Working on New Osteoporosis Drugs