An Emergency Room Visit Is Made for a 42-Year-Old Male

An emergency room visit is made for a 42-year-old male who is experiencing nausea, vomiting, and impaired vision. After tasting the first few ounces of the distillate while manufacturing his own whiskey in a home moonshine still, he began to feel nauseous. Optic disc hyperemia is discovered via funduscopy. Results from the lab indicate a metabolic acidosis with a substantial anion gap. It is discovered that the patient's symptoms are brought on by alcohol dehydrogenase's enzymatic conversion of methanol into formate. Fomepizole, a drug that momentarily binds to alcohol dehydrogenase and stops methanol from reaching the enzyme's active site, is begun in his treatment. Which of the following graphs most accurately portrays the change in enzyme kinetics after administration of the antidote?(Black curves = before treatment)

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