The effects of cortisol on vascular reactivity are studied in a series of experiments in hypophysectomized rats. Their preliminary research demonstrates that administering cortisol by itself does not cause a vascular response. After that, the scientists assess the vascular response to an injection of norepinephrine both with and without a cortisol pretreatment. The graph below displays the outcomes of their experiments. Which of the following pharmacologic principles best describes the effect of cortisol in this experiment?

Question

The effects of cortisol on vascular reactivity are studied in a series of experiments in hypophysectomized rats. Their preliminary research demonstrates that administering cortisol by itself does not cause a vascular response. After that, the scientists assess the vascular response to an injection of norepinephrine both with and without a cortisol pretreatment. The graph below displays the outcomes of their experiments.  Which of the following pharmacologic principles best describes the effect of cortisol in this experiment?

Quizplus · Accepted Answer

Eductional Objective: A permissive hormone doesn't have any impact on a physiological process on its own, but it allows another hormone to have the most impact possible on it. In addition to potentiating vasoconstriction and bronchodilation, cortisol also has a permissive influence on catecholamines, glucagon, and the release of glucose from the liver.

The Effects of Cortisol on Vascular Reactivity Are Studied in a Series