A pharmaceutical firm creates two distinct oral formulations of a novel nonsteroidal anti-inflammatory medicine that is currently under development. Average plasma drug levels are tracked throughout the course of the following 12 hours after two groups of volunteers have received a different formulation. The outcomes are displayed below. Compared to the red curve, the formulation represented by the blue curve is most likely to have which of the following characteristics?

Question

A pharmaceutical firm creates two distinct oral formulations of a novel nonsteroidal anti-inflammatory medicine that is currently under development. Average plasma drug levels are tracked throughout the course of the following 12 hours after two groups of volunteers have received a different formulation. The outcomes are displayed below.  Compared to the red curve, the formulation represented by the blue curve is most likely to have which of the following characteristics?

Quizplus · Accepted Answer

Eductional Objective: Sustained-release drug preparations have reduced and delayed peak levels compared to immediate-release preparations due to slower absorption in the gastrointestinal tract.  Dampening of peak levels and prolonged absorption of the drug help maintain effective drug levels while minimizing toxicity.

A Pharmaceutical Firm Creates Two Distinct Oral Formulations of a Novel