A 50-year-old woman with stage IV chronic kidney disease comes to the office due to persistent high phosphorus level, she tried to restrict phosphorus diet intake but didn't help. Laboratory results are as follows: Treatment with sevelamer is initiated. This medication reduces the serum phosphorus level by which of the following mechanisms?

Question

A 50-year-old woman with stage IV chronic kidney disease comes to the office due to persistent high phosphorus level, she tried to restrict phosphorus diet intake but didn't help. Laboratory results are as follows:  Treatment with sevelamer is initiated. This medication reduces the serum phosphorus level by which of the following mechanisms?

Quizplus · Accepted Answer

Eductional Objective: Chronic kidney disease can cause hyperphosphatemia due to decreased renal excretion of phosphorus.  Dietary phosphorus restriction is recommended, but oral phosphate binders are often needed.  Sevelamer is a nonabsorbable anion-exchange resin that binds intestinal phosphate to reduce absorption.

A 50-Year-Old Woman with Stage IV Chronic Kidney Disease Comes