A 30-year-old women is brought to the emergency department due to multiple episodes of vomiting with lower abdominal pain. She also reports that she hasn't have menstrual cycle for 7 weeks . A urine pregnancy test is positive. The patient has idiopathic pulmonary hypertension complicated by Eisenmenger syndrome. She is aware that pregnancy poses a major mortality risk to herself and the fetus due to the hemodynamic changes of gestation, labor, and delivery. The patient consents to pregnancy termination with a mifepristone and misoprostol regimen. Which of the following is the mechanism of action for mifepristone in this clinical situation?

Question

A 30-year-old women is brought to the emergency department due to multiple episodes of vomiting with lower abdominal pain. She also reports that she hasn't have menstrual cycle for 7 weeks . A urine pregnancy test is positive. The patient has idiopathic pulmonary hypertension complicated by Eisenmenger syndrome.  She is aware that pregnancy poses a major mortality risk to herself and the fetus due to the hemodynamic changes of gestation, labor, and delivery.  The patient consents to pregnancy termination with a mifepristone and misoprostol regimen.  Which of the following is the mechanism of action for mifepristone in this clinical situation?

Quizplus · Accepted Answer

Eductional Objective: Progesterone is necessary for implantation and maintenance of pregnancy.  Mifepristone is a progesterone antagonist that is used with misoprostol (a prostaglandin-E1 agonist) to terminate a first-trimester pregnancy.

A 30-Year-Old Women Is Brought to the Emergency Department Due