An 18-year-old male is brought to the emergency department by his mother after she found him unresponsivenss. She reports that he has been diagnosed with depression after an admission to the psychiatric hospital a week ago. The patient's medications are unknown. Temperature is 38.3 C (100.9 F), blood pressure is 92/49 mm Hg, and pulse is 128/min. On examination, the patient is sedated and disoriented. The pupils are dilated and bowel sounds are decreased. She has 700 mL of urine return when a urinary catheter is placed. ECG reveals sinus tachycardia and a QRS duration of 130 msec. Which of the following is the most likely cause of this patient's symptoms?

Question

An 18-year-old male is brought to the emergency department by his mother after she found him unresponsivenss. She reports that he has been diagnosed with depression after an admission to the psychiatric hospital a week ago. The patient's medications are unknown.  Temperature is 38.3 C (100.9 F), blood pressure is 92/49 mm Hg, and pulse is 128/min.  On examination, the patient is sedated and disoriented.  The pupils are dilated and bowel sounds are decreased.  She has 700 mL of urine return when a urinary catheter is placed.  ECG reveals sinus tachycardia and a QRS duration of 130 msec.  Which of the following is the most likely cause of this patient's symptoms?

Quizplus · Accepted Answer

Eductional Objective: Symptoms of tricyclic antidepressant overdose include seizures, anticholinergic toxicity, hypotension, and cardiac toxicity (eg, QRS widening, ventricular arrhythmias).

An 18-Year-Old Male Is Brought to the Emergency Department by His