Velcade has been used to treat patients with myeloma in part because of its inhibition of

Name: Velcade has been used to treat patients with myeloma in part because of its inhibition of
Brand: Quizplus
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Question

Quizplus · Accepted Answer

Velcade (bortezomib) inhibits the proteasome, leading to inhibition of NF-κB signaling. NF-κB is a transcription factor involved in regulating cell survival and proliferation, and is commonly activated in myeloma cells. By inhibiting NF-κB, Velcade induces apoptosis (cell death) in myeloma cells.

Velcade Has Been Used to Treat Patients with Myeloma in Part