Therapeutic antibodies used in the treatment of cancer are targeted at proteins located

Question

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Therapeutic antibodies used in the treatment of cancer are designed to target proteins that are overexpressed or mutated on the surface of cancer cells. Targeting proteins on normal cells can result in off-target effects and toxicity, so antibodies are specifically designed to avoid normal cells. Proteins located in the nucleus or cytoplasm are not typically targeted by therapeutic antibodies as they are not accessible to the antibodies.

Therapeutic Antibodies Used in the Treatment of Cancer Are Targeted