Which of the following classes of anti-cancer agents has been most successful to date?

Question

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Drugs targeted against receptor-associated tyrosine kinases, which are enzymes involved in cell signaling and growth, have been the most successful class of anti-cancer agents to date. Examples include imatinib for chronic myeloid leukemia and trastuzumab for HER2-positive breast cancer. Low-molecular-weight compounds and antibodies against cancer cells have also shown some success, but not to the same extent as drugs targeting tyrosine kinases. Antibiotics are not typically used as anti-cancer agents.

Which of the Following Classes of Anti-Cancer Agents Has Been