DNA from human lung tumor cells was used to transfect NIH 3T3 mouse embryo fibroblast)cells.After several weeks,some of these cells formed foci,or clusters of cells,on the plate.Cells isolated from these foci were able to grow in soft agar and formed tumors when injected subcutaneously into immunocompromised mice.These results suggest that
A)The oncogene present in the human lung tumor cells is also able to transform NIH 3T3 mouse cells.
B)The NIH 3T3 cells were most likely transformed by multiple oncogenes present in the donor cells.
C)The NIH 3T3 cells were most likely transformed by a single oncogene present in the donor cells.
D)A and C.
E)A,B,and C.

Question

Quizplus · Accepted Answer

The ability of the NIH 3T3 cells to form foci, grow in soft agar, and induce tumors in mice after being transfected with DNA from human lung tumor cells indicates that the oncogene(s) from the human cells can indeed transform the mouse cells, suggesting both A and C are correct. There's no specific evidence provided that multiple oncogenes are required for transformation, making B speculative without further data.

DNA from Human Lung Tumor Cells Was Used to Transfect