The Consequence of Allelic Exclusion at the Immunoglobulin Loci Ensures

The consequence of allelic exclusion at the immunoglobulin loci ensures that _____.(Select all that apply.)

A) B-cell receptors have a low-avidity binding
B) B cells express antigen receptors of a single specificity
C) hybrid immunoglobulins are formed
D) all functional copies of a gene are expressed
E) homogeneous B-cell receptors bind more effectively to antigen.