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Use Your Knowledge of Amino Acid Characteristics to Order the Peptides

Question 56

Essay

Use your knowledge of amino acid characteristics to order the peptides below according to the net charge contributed by their side chains at physiological pH (~pH7).Each peptide contains eight amino acids.Use the single-letter amino acid designations to generate your list, placing the most negatively charged peptide on the left and the most positively charged peptide on the right.In addition, for each peptide, list the total number of positive and negative charges.Remember that, at neutral pH, the amino terminus carries a positive charge and the carboxyl terminus carries a negative charge.
A.YGAKKRA
B.ARRKSTRK
C.DERKQNST
D.DDAEIYSA
E.NQSTYEEG

Correct Answer:

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(D) This peptide has 4 negative charges ...

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