Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
A) A need to monitor drugs metabolized by 2D6 for toxicity
B) Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors
C) Decreased conversion of codeine to morphine by CYP2D6
D) The need for lowered dosages of drugs, such as beta blockers
Correct Answer:
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Q2: Inhibition of P-glycoprotein by a drug such
Q3: Carbamazepine has a black box warning recommending
Q4: Rifampin is a nonspecific CYP450 inducer that
Q5: Genetic polymorphisms account for differences in metabolism,
Q6: Warfarin resistance may be seen in patients
Q7: Genetic testing for a VKORC1 mutation to
Q8: Ultra-rapid metabolizers of drugs may have:
A)To have
Q10: Pharmacogenetic testing is required by the U.S.
Q11: A provider may consider testing for CYP2D6
Q12: Patients who have a poor metabolism phenotype
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