A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to:
A) Ensure the patient will not have increased adverse drug reactions to the tamoxifen
B) Identify potential drug-drug interactions that may occur with tamoxifen
C) Reduce the likelihood of therapeutic failure with tamoxifen treatment
D) Identify poor metabolizers of tamoxifen
Correct Answer:
Verified
Q2: Inhibition of P-glycoprotein by a drug such
Q3: Carbamazepine has a black box warning recommending
Q4: Rifampin is a nonspecific CYP450 inducer that
Q5: Genetic polymorphisms account for differences in metabolism,
Q6: Warfarin resistance may be seen in patients
Q7: Genetic testing for a VKORC1 mutation to
Q8: Ultra-rapid metabolizers of drugs may have:
A)To have
Q9: Up to 21% of Asians are ultra-rapid
Q10: Pharmacogenetic testing is required by the U.S.
Q12: Patients who have a poor metabolism phenotype
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