Carbamazepine Has a Black Box Warning Recommending Testing for the HLA-B*1502

Carbamazepine has a black box warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:

A) Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele
B) Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele
C) Increased risk for Stevens-Johnson syndrome in Asian patients with the HLA-B*1502 allele
D) Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine