Rifampin is a nonspecific CYP450 inducer that may:
A) Lead to toxic levels of rifampin and so must be monitored closely
B) Cause toxic levels of drugs, such as oral contraceptives, when coadministered
C) Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic failure
D) Cause nonspecific changes in drug metabolism
Correct Answer:
Verified
Q1: A genetic variation in how the metabolite
Q2: Inhibition of P-glycoprotein by a drug such
Q3: Carbamazepine has a black box warning recommending
Q5: Genetic polymorphisms account for differences in metabolism,
Q6: Warfarin resistance may be seen in patients
Q7: Genetic testing for a VKORC1 mutation to
Q8: Ultra-rapid metabolizers of drugs may have:
A)To have
Q9: Up to 21% of Asians are ultra-rapid
Q10: Pharmacogenetic testing is required by the U.S.
Q11: A provider may consider testing for CYP2D6
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