Question 1

Which is the most commonly used variety of cannabis?
A) Cannabis sativa
B) Cannabis indica
C) Cannabis gracilis
D) Cannabis ruderalis

Accepted Answer

Cannabis sativa is the most commonly used variety of cannabis, known for its widespread use both recreationally and medicinally around the world.

Question 2

Cannabis may be inhaled through water-pipe devices or less elaborate pipes, referred to as ____, respectively.
A) roaches or bongs
B) roaches or joints
C) hookahs or bongs
D) hookahs or joints

Accepted Answer

Cannabis can be inhaled through more elaborate water-pipe devices known as hookahs, or through less elaborate pipes referred to as bongs.

Question 3

How do anandaminde and 2-AG differ from most other neurotransmitters?
A) They are not metabolized.
B) They are not stored in vesicles.
C) They do not bind to a receptor.
D) They are synthesized in the nucleus.

Accepted Answer

Anandamide and 2-AG differ from most other neurotransmitters because they are not stored in vesicles. Instead, they are synthesized on demand from cell membrane lipid precursors and released immediately.

Question 4

Research associate Dr. Sanchez would like to prevent the breakdown of 2-AG into inactive compounds. Which enzyme should she target?
A) NAPE phospholipase D
B) sn-1-diacyglycerole lipase
C) Monoacylglycerol lipase
D) FAAH

Accepted Answer

The answer of Research associate Dr. Sanchez would like to...

Question 5

Which statement best reflects changing social attitudes regarding the use of marijuana?
A) Cannabis abuse decreased in the late 1950s.
B) The Pharmacopoeia of the United States of America began excluding cannabis from its compilation of medicines after 1942.
C) Although the U.S. government began search and seizure operations at the U.S.-Mexico border in 1969, cannabis smugglers were mostly ignored.
D) As of 2011, current DEA Administrator Michele M. Leonhart is in strong support of lowering the scheduling of cannabis.

Accepted Answer

The exclusion of cannabis from the Pharmacopoeia of the United States of America after 1942 reflects changing social and medical attitudes towards marijuana, indicating a move away from its acceptance as a medicinal substance.

Question 6

Dr. Daly studies how endocannabinoid neurotransmitters interact with neuronal receptors. What neurotransmitters is she likely to study?
A) dronabinol and 2-AG
B) dronabinol and 15d-PG2
C) anandamide and 2-AG
D) anandamide and 15d-PG2

Accepted Answer

Anandamide and 2-AG (2-arachidonoylglycerol) are endogenous cannabinoids, or endocannabinoids, that naturally occur in the body and interact with cannabinoid receptors in the brain and nervous system.

Question 7

For both recreational and instrumental purposes, users most often administer cannabis ____.
A) orally or by inhaling
B) orally or by insufflation
C) injection or inhaling
D) injection or insufflation

Accepted Answer

Cannabis is most commonly consumed orally (in the form of edibles or oils) or by inhaling (smoking or vaporizing), as these methods allow for effective delivery of its active compounds.

Question 8

The activation of cannabinoid receptors leads to various behavioral and psychologica effects by activating CB₁ and CB₂ receptors. What are the characteristics of these receptors? A) ionotropic and excitatory B) ionotropic and inhibitory C) metabotropic and excitatory D) metabotropic and inhibitory

Accepted Answer

Cannabinoid receptors, including CB1 and CB2, are metabotropic, meaning they are G-protein coupled receptors, and primarily have an inhibitory effect on neurotransmitter release, thus leading to various behavioral and psychological effects.

Question 9

What is cannabis's key psychoactive ingredient? A) Δ⁹-THC B) Δ⁸-THC C) cannabidiol D) cannabinol

Accepted Answer

Δ⁹-THC (delta-9-tetrahydrocannabinol) is the primary psychoactive component of cannabis responsible for its intoxicating effects.

Question 10

The various behavioral and physiological effects described for cannabinoids and endocannabinoids result from actions at cannabinoid receptors, such as the CB₁ and CB₂ receptors. What type of receptors are CB₁ and CB₂? A) CB₁ is ionotropic; CB₂ is ionotropic. B) CB₁ is metabotropic; CB₂ is metabotropic. C) CB₁ is ionotropic; CB₂ is metabotropic. D) CB₁ is metabotropic; CB₂ is ionotropic.

Accepted Answer

Both CB1 and CB2 receptors, which are implied by the placeholders CB₁ and CB₂, are metabotropic receptors. They are G protein-coupled receptors, not ionotropic receptors.

Question 11

A condensed preparation of cannabis that primarily contains the trichome resins from the plant is referred to as ____.
A) reefer
B) weed
C) potiguaya
D) hashish

Accepted Answer

Hashish is the correct term for a condensed preparation of cannabis that primarily contains the trichome resins from the plant. It is made by compressing and processing parts of the cannabis plant, particularly the trichomes, to create a concentrated form of cannabis.

Question 12

The use of cannabis in modern medicine largely began from the efforts of ____.
A) Shen-Nung
B) al-Hasan ibn al-Sabbah
C) William O'Shaughnessy
D) Marco Polo

Accepted Answer

William O'Shaughnessy is credited with introducing the therapeutic use of cannabis to Western medicine in the 19th century. His research and advocacy helped pave the way for the modern medicinal use of cannabis.

Question 13

Research associate Dr. Blake would like to prevent the breakdown of anandamide into inactive compounds. Which enzyme should he target?
A) NAPE phospholipase D
B) sn-1-diacyglycerole lipase
C) Monoacylglycerol lipase
D) FAAH

Accepted Answer

FAAH (Fatty Acid Amide Hydrolase) is the enzyme responsible for the breakdown of anandamide into inactive compounds. Inhibiting FAAH would prevent the degradation of anandamide, thus potentially increasing its levels and effects.

Question 14

Herbal marijuana alternatives are ____. A) laboratory-synthesized cannabinoid receptor agonists B) cannabis plants that have been modified to no longer contain Δ⁹-THC C) other psychoactive plants that are typically stronger than cannabis D) safer natural alternatives to cannabis

Accepted Answer

Herbal marijuana alternatives are typically laboratory-synthesized cannabinoid receptor agonists, often referred to as synthetic cannabinoids, which mimic the effects of THC, the active compound in cannabis.

Question 15

Cannabis is included in which schedule, as designated by the DEA?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV

Accepted Answer

Cannabis is classified as a Schedule I substance by the DEA, indicating it is considered to have a high potential for abuse and no accepted medical use in the United States.

Question 16

Johanna smokes marijuana. How long will Δ9-THC be detectable in her body?
A) one day
B) seven days
C) 14 days
D) 30 days

Accepted Answer

Δ9-THC, the active component in marijuana, can be detected in the body for up to 30 days after use, depending on factors such as the frequency of use, body fat, and metabolism.

Question 17

According to the World Health Organization, approximately what percent of the world's population consumes cannabis on a regular basis?
A) 0.5%
B) 2.5%
C) 12.5%
D) 25%

Accepted Answer

According to the World Health Organization, approximately 2.5% of the global population consumes cannabis on a regular basis.

Question 18

Small hairlike structures with glands that release a resin containing a number of phytocannabinoids are called ____.
A) panicles
B) trichomes
C) racemes
D) calyxes

Accepted Answer

Trichomes are small hairlike structures found on plants, including cannabis, that contain glands which release resin rich in phytocannabinoids. These compounds are responsible for many of the plant's effects and therapeutic benefits.

Question 19

Δ⁹-THC exhibits high lipid solubility. How does this impact its effects? A) This leads to slow distribution in tissues. B) This decreases its elimination time. C) Δ⁹-THC becomes sequestered in fat, leading to long-term pharmacological actions D) Δ⁹-THC becomes sequestered in fat, making it less effective

Accepted Answer

High lipid solubility means that Δ⁹-THC can be stored in fat tissues, which can prolong its pharmacological effects as it is slowly released back into the bloodstream over time.

Question 20

The United States first criminalized cannabis for nonmedical purposes in ____.
A) 1927
B) 1937
C) 1947
D) 1957

Accepted Answer

The United States first criminalized cannabis for nonmedical purposes in 1937 with the Marihuana Tax Act.

Quiz 11: Cannabinoids

Which is the most commonly used variety of cannabis?

Cannabis may be inhaled through water-pipe devices or less elaborate pipes, referred to as ____, respectively.

How do anandaminde and 2-AG differ from most other neurotransmitters?

Research associate Dr. Sanchez would like to prevent the breakdown of 2-AG into inactive compounds. Which enzyme should she target?

Which statement best reflects changing social attitudes regarding the use of marijuana?

Dr. Daly studies how endocannabinoid neurotransmitters interact with neuronal receptors. What neurotransmitters is she likely to study?

For both recreational and instrumental purposes, users most often administer cannabis ____.

The activation of cannabinoid receptors leads to various behavioral and psychologica effects by activating CB1 and CB2 receptors. What are the characteristics of these receptors?

What is cannabis's key psychoactive ingredient?

The various behavioral and physiological effects described for cannabinoids and endocannabinoids result from actions at cannabinoid receptors, such as the CB1 and CB2 receptors. What type of receptors are CB1 and CB2?

A condensed preparation of cannabis that primarily contains the trichome resins from the plant is referred to as ____.

The use of cannabis in modern medicine largely began from the efforts of ____.

Research associate Dr. Blake would like to prevent the breakdown of anandamide into inactive compounds. Which enzyme should he target?

Herbal marijuana alternatives are ____.

Cannabis is included in which schedule, as designated by the DEA?

Johanna smokes marijuana. How long will Δ9-THC be detectable in her body?

According to the World Health Organization, approximately what percent of the world's population consumes cannabis on a regular basis?

Small hairlike structures with glands that release a resin containing a number of phytocannabinoids are called ____.

Δ9-THC exhibits high lipid solubility. How does this impact its effects?

The United States first criminalized cannabis for nonmedical purposes in ____.

The activation of cannabinoid receptors leads to various behavioral and psychologica effects by activating CB₁ and CB₂ receptors. What are the characteristics of these receptors?

The various behavioral and physiological effects described for cannabinoids and endocannabinoids result from actions at cannabinoid receptors, such as the CB₁ and CB₂ receptors. What type of receptors are CB₁ and CB₂?

Δ⁹-THC exhibits high lipid solubility. How does this impact its effects?