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Imagine a Chromosome Translocation Event That Brings a Gene Encoding

Question 28

Multiple Choice

Imagine a chromosome translocation event that brings a gene encoding a histone acetyl transferase enzyme from its original chromosomal location to a new one near heterochromatin. Which of the following scenarios is definitely NOT going to happen?


A) The gene gets silenced due to heterochromatin expansion, leading to the misregulation of gene expression for a number of critical genes.
B) The translocation event also brings along a chromatin barrier that can prevent heterochromatin expansion into the gene, and there is no phenotypic anomaly.
C) Since the gene encodes a histone acetyl transferase, it resists heterochromatin expansion by acetylating its own histones.
D) The level of the gene product decreases due to a position effect, leading to an imbalance in the chromatin state of the cell that results in the activation of programmed cell death.

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