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A Research Group Characterized Regions of DNA Within Chromatin from Mouse

Question 97

Multiple Choice

A research group characterized regions of DNA within chromatin from mouse cells. They also characterized the histones flanking these regions. The table below summarizes some of their results.
 DNA  region  DNAse sensitivity  of region  Modification of nearest  histone  I  Yes  Monomethylated lysines  II  Yes  Trimethylated lysines  III  No  None  IV  Yes  Monomethylated lysines \begin{array} { | c | c | c | } \hline \begin{array} { c } \text { DNA } \\\text { region }\end{array} & \begin{array} { c } \text { DNAse sensitivity } \\\text { of region }\end{array} & \begin{array} { c } \text { Modification of nearest } \\\text { histone }\end{array} \\\hline \text { I } & \text { Yes } & \text { Monomethylated lysines } \\\hline \text { II } & \text { Yes } & \text { Trimethylated lysines } \\\hline \text { III } & \text { No } & \text { None } \\\hline \text { IV } & \text { Yes } & \text { Monomethylated lysines } \\\hline\end{array} Which statement provides a plausible hypothesis based on these data?


A) Regions I and IV are promoters.
B) Region III is an enhancer.
C) Region II is a promoter.
D) Regions I, II, and IV are genes under active transcription.

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