Which method would best determine posttranslational modifications to a protein, such as phosphorylation?
A) Tandem mass spectrometry
B) Mass spectrometry
C) Two-dimensional gel electrophoresis
D) Immunoprecipitation

Question

Quizplus · Accepted Answer

Tandem mass spectrometry is the most suitable method for determining posttranslational modifications to a protein, including phosphorylation. This is because it allows for the identification and sequencing of peptides, which can aid in determining the specific location of modifications on the protein.

Which Method Would Best Determine Posttranslational Modifications to a Protein