Which of the following methods would be best for direct determination of the relative level of all mRNAs in a given cell or tissue?
A) Mass spectrometry
B) Immunoprecipitation
C) DNA microarray
D) Two-dimensional gel electrophoresis

Question

Quizplus · Accepted Answer

DNA microarray technology is used to measure the relative expression of thousands of genes simultaneously. This method involves hybridizing labeled cDNA probes from the sample of interest to immobilized DNA probes on a glass slide or chip. The fluorescence intensity of the hybridized probes provides a measure of the relative abundance of each mRNA in the sample. Therefore, DNA microarray is the best method for direct determination of the relative level of all mRNAs in a given cell or tissue.

Which of the Following Methods Would Be Best for Direct