The primary cellular abnormalities in AD are _______ and _______. These abnormalities are seen largely in _______ cortex.

Question

Quizplus · Accepted Answer

The primary cellular abnormalities in AD are neurofibrillary tangles and amyloid plaques. These abnormalities are seen largely in the frontotemporal association cortex. Option A is incorrect because amyloid precursor protein only leads to amyloid plaques and not neurofibrillary tangles. Option C is incorrect because it suggests both amyloid precursor protein and neurofibrillary tangles as primary abnormalities, while only one is the primary abnormality. Option D is incorrect because Aβ42 is a type of β-amyloid, which is a component of amyloid plaques, and not a separate abnormality itself.

The Primary Cellular Abnormalities in AD Are _______ and _______

The Primary Cellular Abnormalities in AD Are _ and _