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What Is the Purpose of Adding an Amine Modifier (Such

Question 1

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What is the purpose of adding an amine modifier (such as triethylamine) to the mobile phase when using a silica-based reversed-phase stationary phase for the chromatography of basic compounds?


A) to help dissolve the basic compounds in the mobile phase
B) to adjust the pH of the mobile phase to the desired basic pH
C) to block free silanol sites on the stationary phase from reacting with the basic solutes
D) to establish a flat baseline for spectrophotometric measurements

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