Which of the following statements are correct regarding mutations?
1)Mutations are changes in the base sequence in DNA and may include insertion, deletion, or replacement.
2)Mutations may result in no effect on protein expression or functional activity.
3)Mutations may result in partial or total loss of protein function.
4)Mutations always result in disease.

Question

Quizplus · Accepted Answer

A mutation is a change in a base sequence of the genetic material of an organism by insertion, deletion, or replacement of a base.Mutations may have no effect on protein expression or functional activity.Mutations occurring in intron regions presumably have no effect at all.On the other hand, mutations in regions that code for key functional domains may drastically alter or eliminate protein function.It is the partial or total loss of function that usually results in disease.

Which of the Following Statements Are Correct Regarding Mutations