You are examining the effects of various oxygen concentrations on cultures of erythrocytes. You find that at low O2 pressures there is rapid depletion of a necessary intermediate in the glycolytic pathway. Further analysis of the cells you are culturing indicates that the activity of the lactate dehydrogenase in these cells is extremely low relative to what is expected. Under these hypoxic conditions, which of the following is the most likely rapidly depleted intermediate?
A) ADP
B) citrate
C) FAD
D) glucose 6-phosphate
E) NAD+
Correct Answer:
Verified
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