You are studying the effects of atrial natriuretic factor (ANF) in an experimental animal model. You find that addition of ANP to these animals results in increased activity of a guanylate cyclase. Which of the following is most likely to result from the increased cGMP concentrations in this animal?

Question

Quizplus · Accepted Answer

Increased cGMP concentrations activate protein kinase G, which is a cGMP-dependent protein kinase, leading to various physiological effects.  Production of cGMP, similar to the effects of cAMP production, results in the activation of a specific protein kinase. In the case of cGMP the serine/ threonine kinase is cGMP-dependent protein kinase, PKG.

You Are Studying the Effects of Atrial Natriuretic Factor (ANF)