The main purpose of diapedesis is to:
A) Aid neutrophils in granule release
B) Capture antigens for presentation to lymphocytes
C) Allow immune cells to travel to the site of infection
D) Activate macrophages for more effective phagocytosis

Question

Quizplus · Accepted Answer

Diapedesis is the process by which immune cells leave the circulation and travel to the site of an infection. This process is initiated by the release of chemokines by cells already at the site. In response to the chemokines, endothelial cells upregulate adhesion molecules that grab passing white blood cells, particularly neutrophils (PMNs), and slow them down. The neutrophil then squeezes between endothelial cells and moves through the tissues to the site of infection, guided by the chemokines. The process of diapedesis does not involve antigen capture, granule release, or phagocytosis, but is often a step that follows or precedes these events.

The Main Purpose of Diapedesis Is To