The enymatic rate constant (kcat/Km)of orotidine 5'-phosphate decarboxylase is 6 × 10⁷ M-1s-¹ and the nonenzymatic rate constant (kn)is 3 × 10-¹⁶ s-¹.What is the value of the enzyme's catalytic proficiency? A) 2 x 10²³ M^-1 B) 5 x 10^-24 M C) 12 x 10^-9 M^-1s^-2 D) 8.3 x 10⁷ Ms² E) Cannot calcuate the profeciency without knowing the value Vmax.

Question

Quizplus · Accepted Answer

Catalytic proficiency is calculated as (kcat/Km) / kn. Substituting the given values: (6 × 10⁷ M⁻¹s⁻¹) / (3 × 10⁻¹⁶ s⁻¹) = 2 × 10²³ M⁻¹.

The Enymatic Rate Constant (Kcat/Km)of Orotidine 5'-Phosphate Decarboxylase Is 6