During the development of atherosclerosis, as platelets adhere to the sub-endothelial surfaces, they begin to secrete both adenosine diphosphate (ADP) and:
A) nitric oxide.
B) platelet-derived growth factor.
C) C-reactive protein.
D) plasminogen activator inhibitor.
E) thromboxane A2.

Question

During the development of atherosclerosis, as platelets adhere to the sub-endothelial surfaces, they begin to secrete both adenosine diphosphate (ADP) and:​
A) ​nitric oxide.
B) ​platelet-derived growth factor.
C) ​C-reactive protein.
D) ​plasminogen activator inhibitor.
E) ​thromboxane A2.

Quizplus · Accepted Answer

E  Platelets secrete platelet-derived growth factor (PDGF) which contributes to the proliferation of smooth muscle cells, and thromboxane A2 which promotes platelet aggregation and vasoconstriction during atherosclerosis development.

During the Development of Atherosclerosis, as Platelets Adhere to the Sub-Endothelial