You culture fibroblasts from a patient in the laboratory.In order to up-regulate the LDL receptors in these cells, you should:
A) Add cholesterol esters to the medium.
B) Add excess LDL to the medium.
C) Inhibit HMG-CoA reductase.
D) Inhibit the activity of acyl-CoA-cholesterol acyl transferase (ACAT) .
E) Add cholestyramine.
Correct Answer:
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