Cholestyramine can be used for the treatment of hypercholesterolemia, either alone or in combination with a statin.Which enzyme is most immediately affected by cholestyramine treatment?

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Cholestyramine is a nonabsorbed ion exchanger that binds bile acids in the small intestine, thus interrupting their enterohepatic circulation.7-Hydroxylase is disinhibited by the lack of bile acids and converts excess cholesterol to bile acids.

Cholestyramine Can Be Used for the Treatment of Hypercholesterolemia, Either