What is a limitation of using pedigrees for positional cloning?
A)Some matings may not be informative.
B)Recombination occurs during meiosis.
C)Pedigrees can be unreliable for many traits.
D)Pedigrees are not based on DNA sequences.

Question

Quizplus · Accepted Answer

Pedigrees may not be informative if the disease-causing mutation is not present in the parents or in individuals who have already died. This limits the ability to track the inheritance of the trait through the pedigree and identify the gene responsible for the condition.

What Is a Limitation of Using Pedigrees for Positional Cloning