How are databases of variants used to help find disease gene candidates?
A)Variants from individuals that do not have the syndrome can be used to eliminate those variants as involved in causing the disease.
B)They can indicate the probability of different variants appearing in a population.
C)Variants from individuals that do not have the syndrome are not useful for this purpose.
D)They can indicate rare variants that will help with the genetic identification of individuals.

Question

Quizplus · Accepted Answer

Databases of variants can be used to eliminate variants as potential disease gene candidates by comparing variants found in individuals without the syndrome. Variants that are not found in affected individuals may not be involved in causing the disease. This can help narrow down the search for disease gene candidates.

How Are Databases of Variants Used to Help Find Disease