When a scientist is attempting to use positional cloning to link a disease-causing allele to a molecular marker, it is important for the marker to be close to the disease-causing allele, otherwise _____ may occur.
A)additional mutation
B)recombination
C)polymorphism
D)locus heterogeneity

Question

Quizplus · Accepted Answer

If the marker is not close to the disease-causing allele, recombination events can occur during meiosis, resulting in shuffling of genetic material between the marker and the allele, making it difficult to link the two.

When a Scientist Is Attempting to Use Positional Cloning to Link