Using metabolism and excretion as the primary factors,select the true statement related to the native and synthetic glucocorticoids.
A) The native and synthetic glucocorticoids are metabolized by the liver and then excreted in the urine.
B) The native and synthetic glucocorticoids are excreted in the urine, and the most common urinary metabolites of cortisol are the 17-hydroxycorticosteroids (17-OHCS) .
C) The native and synthetic glucocorticoid metabolites of cortisol can be measured with a 24-hour urine collection and are used to provide an estimate of glucocorticoid secretion from the adrenal cortex.
D) All of these are correct.
Correct Answer:
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