Question 1

Children with acute lymphoblastic leukemia frequently have chemotherapy (Vincristine)-induced peripheral neuropathy, thus causing range of motion limitations in
A) shoulder flexion.
B) neck rotation.
C) spinal flexion.
D) ankle dorsiflexion.

Accepted Answer

Vincristine is known to cause peripheral neuropathy primarily affecting ankle dorsiflexion and the intrinsic musculature of the feet and hands.

Question 2

Your patient has neutropenia. Neutropenia is the condition of a low absolute neutrophil count. Neutrophils are a type of white blood cell that fights against infection. Absolute neutrophil count (ANC) is a measure of the number of neutrophil granulocytes. When a child is receiving chemotherapy, the physician measures the patient's white blood count regularly, specifically the neutrophils. If an ANC is less than __cells/µL, then the child is considered to have neutropenia and has a significantly increased risk of infection
A) 12,000
B) 3,000
C) 2,000
D) 500

Accepted Answer

Children with ALL receive chemotherapy agents that cause neutropenia. This is when the neutrophil (white blood count) is low and the child is at risk for infection. The physical therapist must take precautions to make sure the toys are clean, and if the physical therapist has a cold/sick, he/she should not work with the patient or should wear a mask.

Question 3

You have been asked to develop an exercise program for a child who has been admitted for a stem cell transplant. Appropriate exercise choices would include
A) wheelchair basketball.
B) resistive weight training.
C) a walking program.
D) All of the above

Accepted Answer

During the period of "conditioning," the child is at a risk for infection, bruising, and fatigue. Wheelchair basketball may put the child at risk for bruising or infection from contact with the other players. Resistive exercise is contraindicated when platelet and white blood cell counts are low. A walking program is therefore the best choice.

Question 4

Common physical therapy interventions for a child with acute lymphoblastic leukemia include
A) orthotics.
B) stretching exercises.
C) age-appropriate strengthening exercises.
D) age-appropriate gross motor developmental activities.
E) All of the above.

Accepted Answer

Children with leukemia often have decreased active and passive ankle dorsiflexion, which may lead to falls during ambulation. An ankle foot orthothis could prevent this issue. Weakness is also a common due to the medical intervention and may require a strengthening program. Finally, the child can develop a gross motor delay in comparison to typically developing peers due to the disease process and the related medical intervention.

Question 5

The most common form of pediatric leukemia is acute lymphoblastic leukemia, which has a survival rate for children between the ages of 1 and 10 years of
A) 80% to 90%.
B) 50% to 60%.
C) 40%.
D) 20%.

Accepted Answer

The survival rate is 80% to 90% for children with acute lymphoblastic leukemia (ALL) between the ages of 1 and 10 years. Prognosis for infants and adolescents with ALL is less favorable.

Question 6

Intrathecal chemotherapy is administered directly into what area?
A) Muscle
B) Mouth
C) Vein
D) Cerebral spinal fluid

Accepted Answer

Because chemotherapy agents often times do not cross the blood-brain barrier, the agents are administered directly into the cerebral spinal fluid.

Quiz 22: Leukemia

Children with acute lymphoblastic leukemia frequently have chemotherapy (Vincristine) -induced peripheral neuropathy, thus causing range of motion limitations in

You have been asked to develop an exercise program for a child who has been admitted for a stem cell transplant. Appropriate exercise choices would include

Common physical therapy interventions for a child with acute lymphoblastic leukemia include

The most common form of pediatric leukemia is acute lymphoblastic leukemia, which has a survival rate for children between the ages of 1 and 10 years of

Intrathecal chemotherapy is administered directly into what area?