The formation of which abnormal hemoglobin can occur in a number of conditions, such as in chronic heavy smokers, and result in the binding of the abnormal molecule to heme 200 times tighter than the binding of oxygen to heme?

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Quizplus · Accepted Answer

Carboxyhemoglobin is the abnormal hemoglobin formed as a result of the binding of carbon monoxide to hemoglobin. Chronic heavy smokers are at a higher risk of forming carboxyhemoglobin due to the inhalation of carbon monoxide-containing smoke. Carboxyhemoglobin binds to heme 200 times tighter than oxygen, leading to reduced oxygen-carrying capacity of the blood and potentially resulting in tissue hypoxia. Methemoglobin and sulfhemoglobin are other types of abnormal hemoglobins but do not have as strong a binding affinity for heme as carboxyhemoglobin.

The Formation of Which Abnormal Hemoglobin Can Occur in a Number