A DNA substitution does not change the amino acid sequence of the protein.This change is thus a _______ substitution.

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A silent substitution is a type of point mutation that does not alter the amino acid sequence of the polypeptide chain. The substitution occurs in the DNA coding sequence, but the resulting protein remains unchanged, as the new codon codes for the same amino acid as the original codon. Silent substitutions are also called synonymous substitutions.

A DNA Substitution Does Not Change the Amino Acid Sequence