The kinetics of a typical CD8 T cell response to an acute virus infection in mice is shown in Figure . and starting at ~day 10 post-infection, the majority of the virus-specific CD8 T cells die. The death of these virus-specific CD8 T cells is caused by:
A) Lysis from the virus infection
B) Engulfment and destruction by phagocytes in the body
C) Destruction by cytotoxic T cells
D) Natural killer cell lysis
E) Fas-induced death or cytokine withdrawal

Question

The kinetics of a typical CD8 T cell response to an acute virus infection in mice is shown in Figure .  and starting at ~day 10 post-infection, the majority of the virus-specific CD8 T cells die. The death of these virus-specific CD8 T cells is caused by:
A) Lysis from the virus infection 
B) Engulfment and destruction by phagocytes in the body 
C) Destruction by cytotoxic T cells 
D) Natural killer cell lysis 
E) Fas-induced death or cytokine withdrawal

Quizplus · Accepted Answer

The death of virus-specific CD8 T cells starting at ~day 10 post-infection is due to Fas-induced death or cytokine withdrawal. This is a normal process of the immune response, as it prevents the accumulation of non-functional or self-reactive T cells.

The Kinetics of a Typical CD8 T Cell Response to an Acute