BCR stimulation and TCR stimulation generally activate similar downstream signaling modules, but do so using related, but not identical, signaling proteins. From the list below, match each B cell protein to its T cell counterpart.
Correct Answer:
Q32: Lymphocyte activation leads to robust proliferation and
Q33: BCR signaling on B cells is initiated
Q34: The mechanism by which CTLA-4 inhibits T
Q35: 'Checkpoint blockade' is a therapeutic strategy based
Q36: In patients with 'CD40 ligand deficiency',
Q37: Wiskott-Aldrich syndrome is an immunodeficiency disease due
Q38: TNF-receptor signaling commonly includes several steps
Q39: An important transcription factor activated by
Q40: The immunosuppressive drug rapamycin acts by inhibiting
Q41: Synthesis question: Co-stimulatory and inhibitory receptors modulate
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