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BCR Stimulation and TCR Stimulation Generally Activate Similar Downstream Signaling

Question 42

Matching

BCR stimulation and TCR stimulation generally activate similar downstream signaling modules, but do so using related, but not identical, signaling proteins. From the list below, match each B cell protein to its T cell counterpart.

Premises:
Syk
BTK
Ig-α or Ig-β
SLP-65
Lyn, Blk or Fyn
CD19/CD21/CD81
Responses:
CD3ζ
PLC-Υ
PI-3-kinase
LAT
ITK
SLP-76
CD28
Vav
ZAP-70
Lck

Correct Answer:

CD3ζ
PLC-Υ
PI-3-kinase
LAT
ITK
SLP-76
CD28
Vav
ZAP-70
Lck
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