'Checkpoint blockade' is a therapeutic strategy based on enhancing T cell responses by inhibiting the function of inhibitory receptors, such as CTLA-4, and PD-1. Patients being treated with these protein-based therapeutics would likely be suffering from:

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Quizplus · Accepted Answer

Checkpoint blockade therapy is used to activate T cells and enhance their responses against cancer cells by blocking inhibitory receptors such as CTLA-4 and PD-1. Therefore, patients being treated with this protein-based therapy are most likely suffering from cancer. It is not typically used for autoimmune, immunodeficiency, inflammatory bowel, or neurodegenerative diseases.

'Checkpoint Blockade' Is a Therapeutic Strategy Based on Enhancing T