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A 60-Year-Old Male Is Admitted to the Hospital After an Infectice

Question 3

Multiple Choice

A 60-year-old male is admitted to the hospital after an infectice endocardaitis diagnosis. As part of the patient's treatment, 240 mg of intravenous gentamicin is started.  The pharmacy calculates that, in this patient, gentamicin has a volume of distribution of 30 L, a half-life of 4 hours, and demonstrates first-order and one-compartment kinetics.  Which of the following is the most likely serum drug concentration just before the next dose 8 hours later?


A) 0) 5 mg/L
B) 1 mg/L
C) 1) 5 mg/L
D) 2 mg/L
E) 3 mg/L

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