A physiologist is studying the mechanisms of signal transduction involved in the pathogenesis of type 2 diabetes mellitus. Their research focuses on the intracellular signaling cascade that begins when insulin binds to the insulin receptor. In a series of experiments, they demonstrate that pre-treatment with tumor necrosis factor alpha (TNF-alph A) results in decreased insulin-mediated glucose uptake. This effect of TNF-alpha is most likely mediated through upregulation of which of the following processes?

Question

A physiologist is studying the mechanisms of signal transduction involved in the pathogenesis of type 2 diabetes mellitus.  Their research focuses on the intracellular signaling cascade that begins when insulin binds to the insulin receptor.  In a series of experiments, they demonstrate that pre-treatment with tumor necrosis factor alpha (TNF-alph A) results in decreased insulin-mediated glucose uptake.  This effect of TNF-alpha is most likely mediated through upregulation of which of the following processes?

Quizplus · Accepted Answer

The Answer is D

A Physiologist Is Studying the Mechanisms of Signal Transduction Involved