You are examining the effects of an experimental compound on the metabolic activities of primary hepatocytes in culture. You discover that addition of your compound to these cells activates changes in metabolic fluxes highly similar to those induced by addition of glucagon. Determination of phosphate incorporation shows that several proteins become hyperphosphorylated following addition of the compound. Which of the following statements would most accurately reflect these changes?
A) glycogen phosphorylase activity will be increased
B) PFK1 activity will be unaffected
C) PFK2 will exhibit an increased level of kinase activity
D) phosphorylase kinase activity will be decreased
E phosphoprotein phosphatase-1 activity will be increased
Correct Answer:
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